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Mold allergy in Adana, Turkey
1Cukurova University Medical Faculty, Department of Pediatric Allergy, Adana, Turkey.
Abstract:
In order to investigate the possible role of molds in respiratory allergy, skin prick tests with the extracts of 19 different fungi were applied to 614 respiratory allergic patients. Indoor mold samples of some of these mold sensitive patients are also presented. Most of the patients (72.6%) had extrinsic asthma while 27.4% having allergic rhinitis. The diagnosis was based on history, clinical examination and skin prick test which was done according to Peppy's method. Aspergillus fumigatus was the most important fungus causing skin test positivity (26.0%). Trichophyton rubrum, Mucor, Penicillium notatum, Aspergillus niger and Alternaria tenius species were also important in decreasing frequencies. A total of 26 species were isolated and Penicillium was the most important one (29.6%). Molds are thought to play an important role as causative agents for allergic rhinitis and asthma.
Insights
This study highlights molds as significant triggers for respiratory allergies. Aspergillus fumigatus and Penicillium species were identified as key fungal culprits in asthma and allergic rhinitis patients.
Area of Science:
- Allergy and Immunology
- Mycology
- Respiratory Medicine
Background:
- Respiratory allergies, including asthma and allergic rhinitis, affect a significant portion of the population.
- Fungal allergens, particularly from molds, are increasingly recognized as important environmental triggers.
Purpose of the Study:
- To investigate the role of various fungi as causative agents in respiratory allergies.
- To identify specific mold species responsible for allergic reactions in patients.
Main Methods:
- Skin prick tests were performed on 614 respiratory allergic patients using extracts from 19 different fungi.
- Diagnosis of allergic conditions was based on patient history, clinical examination, and skin prick testing.
- Indoor mold samples were collected from mold-sensitive patients.
Main Results:
- Aspergillus fumigatus was the most common fungus causing positive skin tests (26.0%).
- Other significant fungi included Trichophyton rubrum, Mucor, Penicillium notatum, Aspergillus niger, and Alternaria tenius.
- Penicillium was the most frequently isolated mold genus (29.6%) from patient environments.
Conclusions:
- Molds play a crucial role as causative agents in allergic rhinitis and asthma.
- Specific fungal species like Aspergillus fumigatus and Penicillium are important allergens for respiratory allergic patients.