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Inducible inhibition of eukaryotic gene expression
R Pescini1, S Alouani, A Proudfoot
1GLAXO Institute for Molecular Biology, Geneva, Switzerland.
Biochemical and Biophysical Research Communications
|August 15, 1994
Abstract:
A regulatable binary expression system for eukaryotes was recently developed based on the tetracycline repressor and its operator. Here we show that this system can be successfully applied to express antisense RNA and completely inhibit gene expression in a tetracycline-repressible fashion.