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[The mechanisms and mediators of ocular inflammation]
1Clinica Oftalmologică Cluj-Napoca.
Abstract:
The humoral and cellular immunity responses are essential components of the inflammation. The inflammation mediators are substances existent in the extracellular medium which achieve the communication between different cells that participate at the inflammatory of immunologic reaction. The humoral mediators (the complement, chinine, coagulation and fibrinolysis systems) come from the activation by other mediators of inactive humoral precursors. The cellular mediators (histamine, serotonin, arachidonic acid metabolites, lymphokines) are freed by cells, activated by other mediators. Some are performed in these cells, other are neoformed. An important role during ocular inflammation is played by oxygen free radicals and bacterial endotoxins.
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