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Surgical infections in children

A M Kosloske1

  • 1Ohio State University College of Medicine, Columbus.

Current Opinion in Pediatrics
|June 1, 1994
PubMed
Summary

Pediatric surgical infections are a significant cause of mortality. Advances in understanding sepsis and new terminology are crucial for managing these complex infections in children.

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Area of Science:

  • Pediatric Surgery
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Infection is a leading cause of mortality and complications in pediatric surgery.
  • Impaired host resistance in children (e.g., due to prematurity, chemotherapy, or AIDS) increases susceptibility to opportunistic infections.

Purpose of the Study:

  • To review recent advances in five key areas of pediatric surgical infections: sepsis, soft-tissue/wound, chest, abdominal, and miscellaneous/nosocomial infections.
  • To highlight new concepts in sepsis, including its stages and inflammatory mediator interactions.

Main Methods:

  • Review of recent literature, primarily retrospective observational studies.
  • Focus on advancements in understanding sepsis, systemic inflammatory response syndrome, and multiorgan dysfunction syndrome.

Main Results:

  • New terminology clarifies sepsis stages and inflammatory processes.
  • Systemic inflammatory response syndrome can progress to multiorgan dysfunction syndrome, independent of the initial infection.

Conclusions:

  • Understanding sepsis progression is critical for pediatric surgical patients.
  • There is a significant need for prospective, randomized trials to guide optimal management and prevention strategies for pediatric surgical infections.

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