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Related Experiment Videos

Silicon ribbon cables for chronically implantable microelectrode arrays

J F Hetke1, J L Lund, K Najafi

  • 1Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor 48109.

IEEE Transactions on Bio-Medical Engineering
|April 1, 1994
PubMed
Summary

Researchers developed miniature, ultraflexible silicon ribbon cables for central nervous system (CNS) microprobes. These durable interconnects enable reliable, long-term chronic recording and stimulation in neurological research.

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Area of Science:

  • Biomedical Engineering
  • Neuroscience
  • Materials Science

Background:

  • Reliable interconnects are crucial for chronic neural recording and stimulation.
  • Existing solutions often lack the flexibility and durability required for in-vivo applications.

Purpose of the Study:

  • To design, fabricate, and test miniature, ultraflexible silicon ribbon cables.
  • To enable robust connections for micromachined silicon microprobes in the central nervous system (CNS).

Main Methods:

  • Fabrication of silicon ribbon cables with varying dimensions (5 µm thick, 1-5 cm long, 60-250 µm wide) and up to eight leads.
  • Electrical characterization of lead resistance and capacitance.
  • Long-term soak testing in buffered saline under electrical and mechanical stress.

Related Experiment Videos

  • In-vivo testing of microprobes with integrated cables in the guinea pig CNS for up to one year.

    • Main Results:

    • Successfully fabricated ultraflexible, strong silicon ribbon cables suitable for surgical manipulation.
    • Achieved low series resistance (4 kΩ/cm for polysilicon, 500 Ω/cm for tantalum) and low capacitance (5-10 pF/cm shunt, <10 fF/cm interlead).
    • Demonstrated subpicoampere leakage levels after over three years of soak testing.
    • Microprobes maintained functionality for up to one year in the CNS, recording neural activity and maintaining 1-7 MΩ impedance.

    Conclusions:

    • Miniature ultraflexible silicon ribbon cables offer a reliable solution for chronic neural interfacing.
    • These interconnects significantly enhance the longevity and performance of CNS microprobes.
    • The developed technology supports advanced applications in neural recording and stimulation.