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A CMOS integrated circuit for multichannel multiple-subject biotelemetry using bidirectional optical transmissions

S Kawahito1, S Ueda, M Ishida

  • 1Department of Information and Computer Sciences, Toyohashi University of Technology, Japan.

IEEE Transactions on Bio-Medical Engineering
|April 1, 1994
PubMed
Summary

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This study introduces a novel CMOS integrated circuit for noninvasive biological signal telemetry, enabling real-time monitoring of multiple subjects in space environments. The system utilizes synchronized optical transmissions for efficient data acquisition during physiological studies.

Area of Science:

  • Biomedical Engineering
  • Space Physiology
  • Integrated Circuit Design

Background:

  • Monitoring physiological signals in space is crucial for understanding the effects of weightlessness.
  • Existing telemetry systems face challenges in multichannel and multi-subject monitoring.
  • Noninvasive methods are preferred for long-term physiological studies.

Purpose of the Study:

  • To develop a compact, low-power CMOS integrated circuit (IC) for a noninvasive biological-signal telemetry system.
  • To enable real-time, multichannel monitoring of multiple subjects during spaceflight.
  • To evaluate the feasibility of synchronized multiple-subject optical biotelemetry.

Main Methods:

  • Design and implementation of a CMOS IC featuring digital synchronization, subject selection, time multiplexing, and analog pulse interval modulation (PIM).

Related Experiment Videos

  • Development of bidirectional optical transmission using infrared light for data transfer.
  • Experimental validation using a multichannel telemetry system with two subjects.

    • Main Results:

    • A functional CMOS IC was developed for evaluating implantable telemetry instrument circuit blocks.
    • Preliminary multichannel telemetry from two subjects demonstrated the core functionality of the system.
    • The system supports up to 4 channels and 4 subjects in real-time.

    Conclusions:

    • The developed CMOS IC is suitable for creating small, lightweight, low-power telemetry instruments for animal studies.
    • Synchronized multiple-subject optical biotelemetry is a viable technique for physiological monitoring in space.
    • This technology advances noninvasive biological signal acquisition in microgravity research.