Vitreous amyloidosis without systemic or familial involvement

Vitreous amyloidosis is a rare condition that occurs in some forms of Transthyretin hereditary Amyloidosis, mainly in Familial Amyloidotic Polyneuropathy type I. Vitreous opacities may be the earliest occurring or, in some cases, only symptom of this disorder. In such cases a family history of amyloidosis is usually present. We report on a case of vitreous amyloidosis in an 80-year-old man where there is no evidence of systemic involvement and no family history of amyloidosis.