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Renovascular hypertension

M J Dillon1

  • 1Renal Unit, Hospital for Sick Children, London, UK.

Journal of Human Hypertension
|May 1, 1994
PubMed
Summary
This summary is machine-generated.

Renovascular disease, a cause of secondary hypertension in children, often involves fibromuscular dysplasia. Many cases require medical therapy due to widespread arterial involvement, limiting surgical options.

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Area of Science:

  • Pediatric Nephrology
  • Cardiovascular Medicine
  • Medical Genetics

Background:

  • Renovascular disease accounts for about 10% of secondary hypertension in children.
  • It is frequently linked to neurofibromatosis and other genetic syndromes.
  • Fibromuscular dysplasia is the most common underlying pathology.

Purpose of the Study:

  • To review the diagnostic and therapeutic approaches for pediatric renovascular disease.
  • To highlight the challenges in managing this condition, particularly in cases with bilateral or intrarenal involvement.

Main Methods:

  • Review of current diagnostic imaging and interventional procedures.
  • Analysis of treatment outcomes based on disease extent and pathology.

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Main Results:

  • Diagnostic tools can define the extent of renovascular disease.
  • While surgical cure is possible, many children require ongoing medical management.
  • Bilateral and intrarenal arterial disease significantly impacts treatment choices and outcomes.

Conclusions:

  • Effective diagnosis of pediatric renovascular disease is achievable with current methods.
  • Despite potential surgical interventions, a considerable number of children necessitate long-term medical therapy.
  • The high prevalence of bilateral and intrarenal arterial involvement limits the success of surgical or angioplasty treatments in many pediatric cases.