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Benextramine, an NPY antagonist, improves sexual behavior in male rats
R Poggioli1, A Benelli, R Arletti
1Institute of Pharmacology, University of Modena, Italy.
Neuropeptides
|May 1, 1994
Abstract:
In adult, sexually-experienced male rats, the NPY-antagonist benextramine--at the doses of 5 and 10 mg/kg i.p. and of 50 micrograms/rat i.c.v.--significantly and specifically improved several parameters of copulatory activity. These data may further support the idea that NPY plays a role in the complex regulation of male sexual function, seemingly at the brain level.