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Updated: Aug 10, 2026

Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring
Published on: June 23, 2015
[Multiple heart valve involvement in renal polycystic disease in the adult]
F López Pardo1, A Cabello González, I Moreno Maqueda
1Servicio de Cardiología, Hospital Universitario Virgen del Rocío, Sevilla.
Abstract:
Adult polycystic kidney disease is associated with frequent extrarenal manifestations. Previous studies have reported a increased incidence of cardiovascular abnormalities, in particular of mitral and tricuspid-valve prolapse, and multivalvular incompetence. These findings lends support to the hypothesis that autosomal dominant polycystic kidney disease is a disorder of connective tissue. A mitral-valve prolapse, and multivalvular incompetence was detected in a 75-year old patient with a polycystic kidney disease. The cardiovascular abnormalities published in the literature are review.
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