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[The microflora of the peritoneal exudate in patients with disseminated peritonitis]
Abstract:
In 11 patients with diffuse peritonitis and 39 patients with general peritonitis the microflora of peritoneal exudate and the sensitivity of isolated microorganisms to antimicrobial preparations were studied. The study revealed that in the total number of microorganisms isolated from peritoneal exudate enterobacteria prevailed in patients with diffuse peritonitis and bacteroids, in patients with general peritonitis. Enterobacteria were most sensitive to ciprofloxacin and claforan, while bacteroids, to ciprofloxacin; at the same time 15.4% of the bacteroid strains under study were resistant to ciprofloxacin.
Insights
This study analyzed peritoneal exudate microflora in peritonitis patients. Enterobacteria were common in diffuse peritonitis, while Bacteroides dominated general peritonitis, showing varied antibiotic sensitivities.
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Medicine
Background:
- Peritonitis, an inflammation of the peritoneum, can be classified as diffuse or general.
- Understanding the microbial landscape and antibiotic susceptibility in peritoneal infections is crucial for effective treatment.
Purpose of the Study:
- To investigate the dominant microorganisms in peritoneal exudate for diffuse and general peritonitis.
- To determine the sensitivity of isolated bacteria to key antimicrobial agents.
Main Methods:
- Analysis of peritoneal exudate microflora from 11 patients with diffuse peritonitis and 39 with general peritonitis.
- Culturing and identification of microorganisms.
- Antimicrobial susceptibility testing of isolated strains.
Main Results:
- Enterobacteria were the predominant microorganisms in diffuse peritonitis.
- Bacteroides species were most prevalent in general peritonitis.
- Enterobacteria showed high sensitivity to ciprofloxacin and claforan.
- Bacteroides demonstrated sensitivity to ciprofloxacin, although 15.4% of strains exhibited resistance.
Conclusions:
- Microbial patterns in peritoneal exudate differ between diffuse and general peritonitis.
- Ciprofloxacin is effective against both Enterobacteria and Bacteroides, but resistance in Bacteroides necessitates careful consideration.