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[Interleukin-2 and its use in hemo-proliferative disorders]
1Kliniki Hematologii I.Ch.W. Akademii Medycznej w Gdańsku.
Interleukin 2 (IL-2) is a cytokine which activates cytotoxic cells and stimulates T suppressor cells and may play a role in the treatment of neoplastic disorders. The majority of clinical trials were performed in renal carcinoma and melanoma. Recent studies showed that IL-2 may also play a role in the treatment of hemoproliferative disorders, but its effectiveness was shown mostly in eradication of minimal residual disease after aggressive chemotherapy and/or bone marrow transplantation.
Interleukin 2 (IL-2) is a cytokine which activates cytotoxic cells and stimulates T suppressor cells and may play a role in the treatment of neoplastic disorders. The majority of clinical trials were performed in renal carcinoma and melanoma. Recent studies showed that IL-2 may also play a role in the treatment of hemoproliferative disorders, but its effectiveness was shown mostly in eradication of minimal residual disease after aggressive chemotherapy and/or bone marrow transplantation.