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Should thyroid function be assessed before cardiopulmonary bypass operations?

T H Jones1, S M Hunter, A Price

  • 1Department of Medicine, Northern General Hospital, Sheffield, United Kingdom.

The Annals of Thoracic Surgery
|August 1, 1994
PubMed
Summary
This summary is machine-generated.

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Preoperative thyroid function testing is recommended for patients on thyroxine therapy before cardiac surgery. While many patients show thyroid abnormalities, routine screening for all may not be necessary, as adverse surgical outcomes were not observed.

Area of Science:

  • Cardiology
  • Endocrinology
  • Surgical Science

Background:

  • Thyroid dysfunction is common in the elderly, a demographic frequently undergoing cardiac surgery.
  • Cardiopulmonary bypass can depress thyroid function, potentially impacting myocardial performance.

Purpose of the Study:

  • To assess thyroid function in patients undergoing elective open-heart surgery.
  • To determine the value of preoperative thyroid function testing in this patient group.

Main Methods:

  • Evaluated thyroid function in 116 patients scheduled for elective open-heart procedures.
  • Analyzed preoperative thyroid function test results and correlated them with surgical outcomes.

Main Results:

  • Thyroid function abnormalities were found in 11.2% of patients.

Related Experiment Videos

  • One patient with overt hypothyroidism died postoperatively from a cerebral infarct.
  • Elevated thyrotropin levels with normal thyroxine were noted in 11 patients; one with overtreated hypothyroidism developed atrial fibrillation.
  • Conclusions:

    • Preoperative thyroid function assessment is indicated for patients on thyroxine therapy.
    • Routine thyroid screening for all patients before cardiopulmonary bypass is not clearly justified.
    • Despite a high incidence of abnormal results, no significant adverse effects on surgical outcomes were observed in this study.