Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Surgical timing in aortic regurgitation: left ventricular function analysis by contractility score

P Di Biasi1, A Pajé, M Salati

  • 1Divisione di Chirurgia Toracica e Cardiovascolare, Ospedale Luigi Sacco, Milano, Italy.

The Annals of Thoracic Surgery
|August 1, 1994
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparative efficacy of PD-1 blockade in patients with dMMR/MSI-H metastatic colorectal or gastric cancer: a global retrospective study.

ESMO gastrointestinal oncology·2026
Same author

Is There Room for Liposomal Irinotecan in Biliary Tract Cancer? A Meta-analysis of Randomised Trials.

Clinical oncology (Royal College of Radiologists (Great Britain))·2023
Same author

Encorafenib plus cetuximab with or without binimetinib in patients with BRAF V600E-mutated metastatic colorectal cancer: real-life data from an Italian multicenter experience.

ESMO open·2022
Same author

Strong impact of sarcopenia as a risk factor of survival in resected gastric cancer patients: first Italian report of a Bicentric study.

Updates in surgery·2021
Same author

Role of poorly differentiated cluster in gastric cancer: is it a new prognosis factor?

Scandinavian journal of gastroenterology·2021
Same author

Predictors of incomplete viral response and virologic failure in patients with acute and early HIV infection. Results of Italian Network of ACuTe HIV InfectiON (INACTION) cohort.

HIV medicine·2020

Early aortic valve replacement in patients with aortic regurgitation is crucial. A computer-analyzed contractility score helps determine optimal timing to prevent irreversible left ventricular dysfunction.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Medical Imaging

Background:

  • Aortic regurgitation (AR) can lead to left ventricular (LV) dysfunction.
  • Assessing LV performance is critical for surgical timing in AR patients.

Purpose of the Study:

  • To evaluate the utility of a computer-analyzed contractility score in assessing LV function before and after aortic valve replacement (AVR) in patients with AR.
  • To determine if this score can predict surgical outcomes and guide optimal AVR timing.

Main Methods:

  • Angiographic evaluation of global left ventricular performance in 32 AR patients.
  • Utilized a computer-analyzed contractility scoring system pre- and post-AVR.
  • Categorized patients based on preoperative contractility scores (0-40 vs. >40).

Related Experiment Videos

Main Results:

  • A strong correlation was found between preoperative and postoperative contractility scores.
  • Postoperative scores improved in most patients with preoperative scores <40.
  • Patients with preoperative scores ≥40 showed persistent contractile dysfunction and poor surgical outcomes.

Conclusions:

  • A computer-analyzed contractility score is a valuable tool for assessing LV function in AR.
  • Optimal timing for AVR is essential, ideally before irreversible LV dysfunction occurs.
  • This scoring system may aid in identifying asymptomatic AR patients who would benefit from early AVR.