Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Brucellosis in childhood

L Street, W W Grant, J D Alva

    Pediatrics
    |March 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Brucellosis is an uncommon childhood illness. Pediatricians should consider brucellosis in children with unexplained fever or enlarged liver/spleen, especially after consuming unpasteurized dairy products.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Pelvic Hæmatocele.

    The Chicago medical journal and examiner·2023
    Same author

    Railway Spine and Litigation Symptoms: Presented in the Fourth Annual Meeting of the American Academy of Railway Surgeons at Chicago, Ill., Oct. 6-8, 1897.

    The Southern medical record·2022
    Same author

    Intertriginous mycosis fungoides with T follicular helper cell phenotype progressing to Sézary syndrome.

    Clinical and experimental dermatology·2021
    Same author

    Amniotic fluid index curves in the obese gravida.

    Journal of neonatal-perinatal medicine·2020
    Same author

    Predicting 3-year outcomes of early-identified children with hearing impairment.

    B-ENT·2014
    Same author

    Developing a trust-wide centralised approach to the use of TNP.

    Journal of wound care·2002
    Same journal

    Influenza Vaccine Effectiveness Against Pediatric Death in the United States: 2016-2025.

    Pediatrics·2026
    Same journal

    Averting the Unthinkable: Immunization to Prevent Childhood Deaths From Influenza.

    Pediatrics·2026
    Same journal

    Severe Postoperative Hypernatremia in an Adolescent Following Sleeve Gastrectomy.

    Pediatrics·2026
    Same journal

    Barriers to Implementing SMART for Asthma in Pediatric Primary Care.

    Pediatrics·2026
    Same journal

    Blood Lead Testing Among Children Enrolled in Medicaid.

    Pediatrics·2026
    Same journal

    From Screening to Support: Crafting Social Needs Response Systems That Work for Families.

    Pediatrics·2026
    See all related articles

    Area of Science:

    • Pediatrics
    • Infectious Diseases
    • Microbiology

    Background:

    • Brucellosis is rare in children, with decreasing reports due to animal disease control.
    • Pediatricians may be unfamiliar with the diverse clinical presentations of childhood brucellosis.
    • A cluster of nine pediatric cases in El Paso, Texas, highlighted the disease's protean manifestations.

    Purpose of the Study:

    • To describe the clinical features, diagnosis, and treatment of a brucellosis outbreak in children.
    • To emphasize the importance of considering brucellosis in pediatric patients with obscure fever and hepatosplenomegaly.

    Main Methods:

    • Retrospective review of nine pediatric brucellosis cases.
    • Clinical data collection including symptoms, physical findings, laboratory results, and diagnostic methods.

    Related Experiment Videos

  • Microbiological investigation, including blood and bone marrow cultures.
  • Treatment efficacy assessment based on clinical response to antibiotics.

    • Main Results:

    • Cases presented with spiking fevers, lethargy, tender hepatosplenomegaly, epistaxis, arthralgia, myalgia, and weight loss.
    • Laboratory findings included leukopenia or leukemoid reaction and elevated liver enzymes.
    • Febrile agglutinins were crucial for diagnosis; Brucella was isolated from seven patients.
    • Unusual isolation of Brucella melitensis, linked to consumption of unpasteurized goat's milk cheese from Mexico.
    • All patients showed rapid improvement with a combination of oral tetracycline and intramuscular streptomycin.

    Conclusions:

    • Brucellosis presents with varied symptoms in children, including fever and hepatosplenomegaly.
    • Prompt diagnosis relies on clinical suspicion, serological tests (febrile agglutinins), and prolonged blood/bone marrow cultures.
    • Consumption of unpasteurized dairy products is a significant risk factor, necessitating pediatrician awareness in endemic or risk areas.