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Measles immunisation in children with allergy to egg
BMJ (Clinical Research Ed.)
|July 23, 1994
Summary
Children with egg allergy can safely receive the measles vaccine. Skin testing with the measles vaccine is not necessary to predict adverse reactions in these children.
Area of Science:
- Pediatrics
- Allergy and Immunology
- Vaccinology
Background:
- Egg allergy is common in children, raising concerns about potential adverse reactions to measles vaccination.
- Previous recommendations advised caution or specific testing for measles immunization in children with egg allergy.
Purpose of the Study:
- To assess adverse reactions to measles vaccine in children with egg allergy.
- To determine if intradermal skin testing with measles vaccine predicts adverse reactions.
Main Methods:
- A prospective study of 96 children with egg allergy undergoing measles immunization.
- Intradermal skin testing with measles vaccine was performed in a subset of children.
Main Results:
- Minor adverse reactions occurred in 0.98% of children, with no serious reactions reported.
- Intradermal skin testing with measles vaccine did not accurately predict adverse reactions.
- No children with a positive skin prick test to measles vaccine reacted to the vaccine.
Conclusions:
- Measles vaccination is safe for children with egg allergy.
- Pre-vaccination skin testing with measles vaccine is not indicated.
- Management of measles immunization in allergic children should be handled by specialists.