A cDNA encoding an ADP/ATP carrier from the mosquito Anopheles gambiae

Two cDNAs are described from Anopheles gambiae that correspond to the ADP/ATP carrier or translocase. The clones are identical except for minor differences in the 5' non-coding region and in the lengths of the poly-A tails. They code for mRNAs of 1261 and 1263 bp and contain one open reading frame of 906 bp. A probe made from the 1263 bp cDNA hybridized to bands of approximately 1260 and 1700 bp on developmental Northern blots. The putative 300 amino acid peptide sequence shows from 53.4-78.5% identity to AAC peptide sequences from a range of organisms from Zea mays to human. Both clones mapped to region 26a on the left arm of chromosome 2 in An. gambiae.