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Computer analyses suggest interactions of non-muscle filamin with lipid membranes
M Tempel1, W H Goldmann, G Isenberg
1Technical University of Munich, Garching, Germany.
FEBS Letters
|August 22, 1994
Abstract:
It is concluded from structure predictions of the primary amino acid sequence by computer analyses that two segments of non-muscle filamin could facilitate lipid membrane attachment or anchoring. Residues 49-71 of the amino-terminal may attach to phospholipid membranes, and residues 131-155 may anchor in the hydrophobic region of lipid membranes.