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cAMP-dependent protein phosphorylation in mitochondria of bovine heart
Z Technikova-Dobrova1, A M Sardanelli, M R Stanca
1Institute of Medical Biochemistry and Chemistry, University of Bari, Italy.
FEBS Letters
|August 22, 1994
Abstract:
A study is presented of the cAMP-dependent phosphorylation in bovine heart mitochondria of three proteins of 42, 16 and 6.5 kDa associated to the inner membrane. These proteins are also phosphorylated by the cytosolic cAMP-dependent protein kinase and by the purified catalytic subunit of this enzyme. In the cytosol, proteins of 16 and 6.5 kDa are phosphorylated by the cAMP-dependent kinase. It is possible that cytosolic and mitochondrial cAMP-dependent kinases phosphorylate the same proteins in the two compartments.