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Alkaline reflux gastritis

W P Ritchie1

  • 1Department of Surgery, Temple University Hospital, Philadelphia, Pennsylvania.

Gastroenterology Clinics of North America
|June 1, 1994
PubMed
Summary
This summary is machine-generated.

Alkaline reflux gastritis, a postgastrectomy syndrome, lacks a strong theoretical basis and is diagnosed by exclusion. While some treatments offer modest relief, long-limb Roux-en-Y surgery can eliminate reflux but may cause complications.

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Area of Science:

  • Gastroenterology
  • Surgical Gastroenterology

Background:

  • Alkaline reflux gastritis is theorized as a postgastrectomy syndrome.
  • It is presumed to result from excessive reflux into the residual stomach after peptic ulcer surgery.

Purpose of the Study:

  • To critically examine the theoretical basis for alkaline reflux gastritis.
  • To review diagnostic and therapeutic approaches for this condition.

Main Methods:

  • Critical review of existing literature and theoretical frameworks.
  • Analysis of diagnostic criteria and treatment outcomes.

Main Results:

  • The theoretical basis for alkaline reflux gastritis is found to be insufficient.
  • Diagnosis is primarily one of exclusion.

Related Experiment Videos

  • Nonoperative therapies show limited efficacy, with ursodeoxycholic acid as a potential exception.
  • Long-limb (45-cm) Roux-en-Y surgery effectively eliminates reflux but does not invariably resolve symptoms.
  • Surgical complications include marginal ulceration and Roux stasis syndrome.
  • Conclusions:

    • The existence of alkaline reflux gastritis as a distinct syndrome is questionable.
    • Management requires careful consideration of diagnostic exclusion and therapeutic options.
    • Surgical intervention, while effective for reflux, carries its own set of complications.