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Related Experiment Videos

Cognitive behavior therapy for treatment-refractory panic disorder

M H Pollack1, M W Otto, S P Kaspi

  • 1Clinical Psychopharmacology Unit, Harvard Medical School, Massachusetts General Hospital, Boston 02114.

The Journal of Clinical Psychiatry
|May 1, 1994
PubMed
Summary

Cognitive behavior therapy (CBT) can help patients with panic disorder who do not fully respond to medication. This pilot study shows CBT improves symptoms and global function, with benefits maintained at follow-up.

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Area of Science:

  • Psychiatry
  • Clinical Psychology

Background:

  • Panic disorder often has an incomplete response to pharmacotherapy.
  • Many patients remain symptomatic despite medication trials.
  • Inadequate pharmacotherapeutic treatment is a concern.

Purpose of the Study:

  • To assess the efficacy of cognitive behavior therapy (CBT) in patients with panic disorder.
  • To evaluate CBT for individuals with an incomplete response to pharmacotherapy.

Main Methods:

  • Pilot study involving 15 patients with panic disorder.
  • 12-week group cognitive behavior therapy (CBT) intervention.
  • Assessment of panic attack frequency and global outcome at baseline, endpoint, and follow-up.

Main Results:

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  • Significant improvement in global function post-CBT.
  • Reduced panic attack frequency observed.
  • Sustained improvement at 2-month follow-up.

Conclusions:

  • Patients with panic disorder resistant to pharmacotherapy may benefit from CBT.
  • CBT can be an effective addition to pharmacotherapy for panic disorder.
  • Highlights the need for comprehensive treatment strategies for panic disorder.