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Occupational risks for colon cancer in Sweden
W H Chow1, H S Malker, A W Hsing
1National Cancer Institute, Division of Cancer Etiology, Bethesda, MD 20892.
Journal of Occupational Medicine. : Official Publication of the Industrial Medical Association
|June 1, 1994
Summary
This study found that sedentary white-collar jobs may slightly increase colon cancer risk, while active agricultural jobs may decrease it. Occupation
Area of Science:
- Occupational Health
- Cancer Epidemiology
- Environmental Health
Background:
- Colon cancer incidence varies across occupational groups.
- Understanding environmental and occupational risk factors for colon cancer is crucial for public health.
- Previous studies suggest a link between physical activity levels and colon cancer risk.
Purpose of the Study:
- To systematically assess colon cancer incidence in relation to industry and occupation in Sweden.
- To identify specific occupational cohorts with elevated or reduced risk of colon cancer.
- To explore the role of physical activity as an indirect occupational factor in colon cancer etiology.
Main Methods:
- Utilized the Cancer-Environment Registry of Sweden, linking 1960 census data with cancer incidence data from 1961-1979.
- Conducted a population-based cohort study of all employed persons in Sweden.
- Analyzed colon cancer incidence by industry and occupation, including subsite analysis.
Main Results:
- Observed statistically significant excesses of colon cancer among white-collar occupations (administrators, professionals, clerical, sales).
- Found a reduction in colon cancer incidence among agricultural workers (farmers, fishermen, hunters).
- Identified specific excesses in shoe/leather workers, metal smiths, and foundry workers, but overall occupational role appears small, possibly indirect via physical activity.
Conclusions:
- Occupational physical activity levels appear to be a significant indirect factor in colon cancer risk.
- Sedentary white-collar jobs are associated with a slightly elevated colon cancer risk.
- Active agricultural occupations are associated with a reduced colon cancer risk.
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