[In situ ++hybridization with painting probes in the definition of reciprocal translocations]

Standard banding cytogenetic techniques do not always allow to define the size of chromosome rearrangements involving reciprocal translocations. Fluorescent in situ hybridization of chromosome-specific libreries allowed the rapid and unequivocal characterization of three chromosome rearrangements: a reciprocal translocation involving chromosome 11 and 22, an other involving chromosome 5 and 16 and at least a rearrangement involving chromosomes 5 and 11.