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Isolation of a polysaccharide with antiviral effect from Ulva lactuca
V Ivanova1, R Rouseva, M Kolarova
1Institute of Microbiology, Bulgarian Academy of Science, Sofia.
Preparative Biochemistry
|May 1, 1994
Abstract:
A polysaccharide from the green marine algae Ulva lactuca has been isolated. The substance has been investigated after acid hydrolysis by thin-layer and gas chromatography. The following carbohydrate components have been found: arabinose-xylose-rhamnose-galactose-mannose-glucose in ratio 1:1:9:5:2.5:16 respectively. One unidentified sugar has been demonstrated too. The polysaccharide has been studied for antiviral activity in vitro against a number of human and avian influenza viruses. A considerable inhibition of the viral reproduction was found. The effect was dose-dependent, strain-specific and selective.