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A convenient synthesis of new substituted pyrazolo[4,3-c]quinolines with potential antiinflammatory activity
1Chemistry Department, Faculty of Science, Minia University, Egypt.
Die Pharmazie
|July 1, 1994
Abstract:
2,4-Dichloro-quinoline-3-carbonitrile 1 reacts with hydrazines to afford pyrazolo[4,3-c]quinolines 5a, b. The reaction of 5a with sodium azide; hydrogen/Pd; triethylorthoformate; cyclohexylamine; piperidine; morpholine and acetic anhydride resulted in the corresponding heterocyclic derivatives 6-15.