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The ultrastructural morphology of the squirrel monkey area postrema
Cell and Tissue Research
|July 16, 1975
Summary
The squirrel monkey area postrema (AP) contains glial cells, neurons, and modified ependyma. Its prominent vascularity features fenestrated capillaries and perivascular spaces.
Area of Science:
- Neuroscience
- Cell Biology
- Primate Anatomy
Background:
- The area postrema (AP) is a circumventricular organ with chemoreceptive functions.
- Understanding the cellular composition of the AP is crucial for comprehending its role in physiological regulation.
Purpose of the Study:
- To investigate the ultrastructural morphology of the squirrel monkey (Saimiri sciureus) area postrema.
- To identify and characterize the cellular and vascular components of the AP.
Main Methods:
- Transmission electron microscopy was used to examine the fine structure of the AP.
- Cellular elements and vascular features were analyzed at the ultrastructural level.
Main Results:
- The AP primarily consists of two glial cell types and one neuronal type, with neurons often near perivascular spaces.
- Abundant synaptic terminals (axo-somatic and axo-dendritic) were observed, containing both clear-cored and dense-cored vesicles.
- The AP exhibits prominent vascularity with fenestrated capillaries, perivascular spaces containing fibroblasts and collagen, and endothelial pinocytotic activity.
Conclusions:
- The squirrel monkey AP is characterized by a unique cellular composition and extensive vascularization.
- The ultrastructure suggests specialized functions related to barrier properties and sensory input/output.