Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Paternity testing in the DNA era

S D Pena1, R Chakraborty

  • 1Núcleo de Genética Médica de Minas Gerais (GENE/MG), Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Trends in Genetics : TIG
|June 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Measurement of the Positive Muon Anomalous Magnetic Moment to 127 ppb.

Physical review letters·2025
Same author

A compact frozen-spin trap for the search for the electric dipole moment of the muon.

The European physical journal. C, Particles and fields·2025
Same author

Molecular characterization and virulence of fungal pathogens associated with mass mortalities in hilsa Shad (Tenualosa ilisha).

Scientific reports·2025
Same author

Anomalous spin precession systematic effects in the search for a muon EDM using the frozen-spin technique.

The European physical journal. C, Particles and fields·2024
Same author

Measurement of the Positive Muon Anomalous Magnetic Moment to 0.20 ppm.

Physical review letters·2023
Same author

Coronavirus peplomer interaction.

Physics of fluids (Woodbury, N.Y. : 1994)·2022

Paternity testing is highly accurate using variable number of tandem repeat (VNTR) polymorphisms. DNA fingerprinting and PCR methods provide certainty in resolving paternity disputes, overcoming statistical challenges.

Area of Science:

  • Forensic Genetics
  • Molecular Biology

Background:

  • Paternity testing relies on genetic markers to establish biological relationships.
  • Variable number of tandem repeat (VNTR) polymorphisms are highly informative genetic markers.

Purpose of the Study:

  • To evaluate the efficiency and effectiveness of VNTR polymorphisms in paternity testing.
  • To assess the reliability of DNA fingerprinting and PCR-based methods for paternity resolution.

Main Methods:

  • Utilizing multi-allelic VNTR polymorphisms.
  • Employing multilocus DNA fingerprinting probes or single-locus minisatellite probes.
  • Performing PCR testing on sets of minisatellite and microsatellite loci.

Main Results:

  • VNTR polymorphisms offer efficient and effective paternity testing.

Related Experiment Videos

  • Multilocus and single-locus probe methods, along with PCR, achieve high informativeness.
  • Paternity disputes can be resolved with near certainty.

    • Conclusions:

    • VNTR polymorphisms are a powerful tool for definitive paternity testing.
    • Despite remaining statistical and population genetics challenges, current methods provide highly reliable results.
    • The high informativeness of hypervariable loci ensures accurate resolution of paternity cases.