[The correlation of the clinical and the computed tomographic changes in patients with atherosclerotic circulatory...

Area of Science:

• Neurology
• Vascular Medicine
• Radiology

Background:

• Atherosclerotic dyscirculatory encephalopathy involves stenotic lesions in major brain arteries.
• Understanding the interplay between hemodynamic, structural, and clinical changes is crucial for patient management.
• Previous research has not fully elucidated the topographic connections between these manifestations.

Purpose of the Study:

• To correlate hemodynamic, structural, and clinical changes in patients with stenotic lesions of major brain arteries.
• To investigate the relationship between vascular aspects and neurological symptoms like paresthesias.
• To analyze the presentation of hydrocephalus in relation to brain atrophy and infarction.

Main Methods:

• Analysis of data from 175 patients with atherosclerotic dyscirculatory encephalopathy.
• Utilized ultrasonic and radioopaque diagnosis for vascular lesions of the head and neck.
• Integrated clinical, neurological observations, and computerized tomography (CT) scan data of the brain.

Main Results:

• Established topographic connections between hemodynamic, structural, and neurological manifestations of the disease.
• Observed that moderately severe hydrocephalus, a sign of brain atrophy, often preceded brain infarction.
• Identified a vascular basis for monotype paresthesias in extremities linked to major artery lesions.

Conclusions:

• Hemodynamic and structural changes in major brain arteries significantly correlate with clinical and neurological outcomes.
• Early detection of hydrocephalus may indicate significant brain atrophy and increased risk of infarction.
• Vascular assessments are vital for understanding and managing neurological symptoms associated with peripheral artery disease.