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[Diagnosis of steatorrhea]
1Medizinische Klinik II, Johann Wolfgang Goethe-Universität Frankfurt/M.
Zeitschrift Fur Gastroenterologie
|May 1, 1994
Summary
This review details various diagnostic methods for steatorrhea, aiding in malabsorption syndrome detection. Understanding these techniques ensures accurate interpretation and a pathophysiological diagnostic approach.
Area of Science:
- Gastroenterology and Clinical Chemistry
- Diagnostic Medicine
Context:
- Malabsorption syndromes require accurate diagnosis through fecal fat analysis.
- Various quantitative and indirect measures exist for detecting steatorrhea.
Purpose:
- To provide a comprehensive overview of traditional, current, and emerging diagnostic methods for steatorrhea.
- To elucidate the rationales, principles, technical aspects, advantages, and limitations of each method.
- To offer practical guidance for selecting appropriate tests based on clinical scenarios and resource availability.
Summary:
- The review covers fecal weight, aspect, microscopy (Sudan stain), steatocrit, serum beta-carotenoids, titrimetric (van de Kamer) and gravimetric analysis.
- It also includes advanced techniques like 14CO2-breath tests, NMR-spectroscopy, near-infrared spectrometric analysis (NIRA), and 13CO2 stable isotope breath tests.
- Prerequisites for application and practical recommendations are provided for diverse diagnostic needs.
Impact:
- Empowers clinicians with knowledge for rational, pathophysiologically-based diagnostic strategies for steatorrhea.
- Facilitates informed selection between low-budget and high-tech methods for assessing fat maldigestion and malabsorption.
- Enhances diagnostic accuracy and patient management in malabsorption syndromes.