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Tacalcitol ointment for psoriasis
M Nishimura1, Y Makino, H Matugi
1Department of Dermatology, Saga Prefect, Hospital Kouseikan, Japan.
Acta Dermato-Venereologica. Supplementum
|January 1, 1994
Abstract:
Transdermal absorption of tacalcitol from the ointment containing 2 micrograms/g was studied using hairless rat and human skin. In the animal experiments, a non-negligible amount of tacalcitol was absorbed transdermally, whereas in the case of human skin, this compound was hardly absorbed at all. A placebo-controlled double-blind right/left comparison confirmed that this ointment is effective and safe for the treatment of psoriasis.