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Colorectal cancer incidence in pattern and model makers: evidence from a screening program
1Division of Epidemiology, Michigan Cancer Foundation, Detroit 48201.
American Journal of Industrial Medicine
|July 1, 1994
Summary
Colorectal cancer screening significantly benefits high-risk individuals. Participation in screening reduced cancer risk by over 10-fold in this automotive pattern and model maker cohort.
Area of Science:
- Occupational Health
- Gastroenterology
- Oncology
Background:
- Automotive pattern and model makers represent a high-risk demographic for colorectal cancer.
- Previous research indicates a need for targeted screening in specific occupational groups.
Purpose of the Study:
- To evaluate the effectiveness of a comprehensive colorectal cancer screening program.
- To assess the impact of screening participation on cancer incidence within a defined high-risk cohort.
Main Methods:
- A cohort of 1,641 white male automotive pattern and model makers was established in 1981.
- Screening included flexible sigmoidoscopy, stool occult blood testing, and digital rectal examination.
- Participants were offered screening periodically from 1981 to 1991.
Main Results:
- Approximately 60% of eligible individuals participated in at least one screening examination.
- Non-participants exhibited a relative risk for incident colorectal cancer exceeding 10 compared to participants.
- Ten years of cohort tracking data suggest a significant benefit of screening.
Conclusions:
- Colorectal cancer screening is effective in reducing cancer incidence in high-risk occupational groups.
- Regular participation in screening programs is crucial for mitigating colorectal cancer risk.
- This study underscores the importance of tailored screening strategies for at-risk populations.