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Avocado hypersensitivity

C Blanco1, T Carrillo, R Castillo

  • 1Department of Allergy, Nuestra Sra. del Pino Hospital, Las Palmas de Gran Canaria, Canary Islands, Spain.

Allergy
|July 1, 1994
PubMed
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Immediate hypersensitivity to avocado affects 17 patients, causing reactions from anaphylaxis to skin rashes. Avocado allergy is often linked to latex, chestnut, and banana allergies due to shared allergens.

Area of Science:

  • Food allergy
  • Immunology
  • Dermatology

Background:

  • Avocado (Av) is a fruit from the Lauraceae family.
  • Immediate hypersensitivity to avocado is increasingly recognized.
  • Cross-reactivity with other allergens is common in avocado-sensitive individuals.

Purpose of the Study:

  • To investigate clinical manifestations of avocado hypersensitivity.
  • To identify associated sensitizations in avocado-allergic patients.
  • To compare the allergenicity of different avocado varieties and explore cross-reactivity.

Main Methods:

  • Patient data collection on clinical reactions to avocado ingestion.
  • Skin prick tests (SPT) performed with Strong avocado variety (SAv) and Hass avocado variety (HAv).

Related Experiment Videos

  • Specific IgE testing using commercial CAP and RAST inhibition assays with various allergen extracts.

    • Main Results:

    • 17 patients reported immediate hypersensitivity to avocado with diverse clinical symptoms.
    • SPT positive for SAv in all patients and HAv in 14 patients.
    • Significant cross-reactivity observed with latex, chestnut, and banana, suggesting common antigenic determinants.

    Conclusions:

    • Avocado hypersensitivity presents with varied symptoms and is frequently associated with latex, chestnut, and banana allergies.
    • Strong avocado variety (SAv) appears more allergenic than Hass avocado variety (HAv).
    • Evidence suggests shared allergens between avocado, latex, chestnut, and banana.