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Synthesis and muscle relaxant activity of cyclic baclofen analogues
G Pifferi1, R Nizzola, A Cristoni
1Istituto di Chimica Farmaceutica e Tossicologica, Università di Milano, Italy.
Farmaco (Societa Chimica Italiana : 1989)
|June 1, 1994
Abstract:
Some new cyclic analogues of baclofen have been prepared and characterized, starting from 4-(4-chlorophenyl)-pyrrolidone. When tested in comparison with the parent compound, they exhibited only a moderate muscle relaxant activity.