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[A possible same genetic defect in two Niemann-Pick disease model mice]

T Yamamoto1, K Iwasawa, T Tokoro

  • 1Department of Pediatrics, Jikei University, School of Medicine, Tokyo.

Summary

Two Niemann-Pick disease mouse models, NCTR-BALB/c and SPM, exhibit deficient cholesterol esterification. Genetic analysis indicates both models share the same genetic deficiency, suggesting a common underlying cause for their Niemann-Pick disease phenotypes.

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