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Related Experiment Videos

Skin lesions in psoriasis

M Goodfield1

  • 1University of Leeds, Yorkshire, UK.

Bailliere'S Clinical Rheumatology
|May 1, 1994
PubMed
Summary
This summary is machine-generated.

Psoriatic skin disease is a common condition affecting skin, scalp, and nails. While treatable with topical therapies, systemic treatments and UV radiation offer control for resistant cases.

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Area of Science:

  • Dermatology
  • Genetics
  • Immunology

Background:

  • Psoriatic skin disease is a prevalent condition affecting all age groups.
  • It frequently co-exists with joint disease in about 10% of patients.
  • Skin lesions are typically recognizable, but atypical forms and unusual sites pose diagnostic challenges for non-specialists.

Purpose of the Study:

  • To provide an overview of psoriatic skin disease, including its clinical presentation, etiology, and management.
  • To highlight the diagnostic difficulties associated with atypical presentations.
  • To discuss treatment strategies and the overall prognosis for patients.

Main Methods:

  • Review of existing literature and clinical observations on psoriatic skin disease.
  • Discussion of genetic and environmental factors contributing to the condition.

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  • Analysis of current therapeutic approaches, including topical treatments, systemic therapies, and ultraviolet radiation.

    • Main Results:

    • Psoriatic skin disease involves skin, scalp, and nails, with variable clinical presentations.
    • The exact cause remains unknown, but genetic predisposition and external factors play significant roles.
    • Topical treatments are effective for most patients; resistant cases benefit from combined systemic therapy and UV radiation.

    Conclusions:

    • Psoriatic skin disease is manageable, with most patients leading normal lives.
    • While not curable, effective treatments exist, and mortality is rare, except in severe forms.
    • The significant social and occupational morbidity associated with the condition is often underestimated.