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Repeated resection of recurrent pulmonary metastatic soft tissue sarcoma
A N van Geel1, H J Hoekstra, F van Coevorden
1Dr Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.
Summary
Repeated thoracotomy is effective for recurrent lung metastases from soft tissue sarcoma (STS). Complete removal of metastases during surgery leads to long-term survival, with no postoperative deaths in this patient series.
Area of Science:
- Oncology
- Thoracic Surgery
- Sarcoma Research
Background:
- Soft tissue sarcoma (STS) can metastasize to the lungs.
- Pulmonary surgery is a treatment for lung metastases.
- Recurrence of lung metastases after surgery poses a challenge.
Purpose of the Study:
- To evaluate the efficacy of repeat thoracotomy for recurrent lung metastases from STS.
- To assess the safety and long-term outcomes of multiple thoracotomies.
Main Methods:
- Retrospective analysis of nine patients with recurrent lung metastases from STS.
- Patients underwent second or further thoracotomy procedures.
- Survival and outcomes were tracked post-operatively.
Main Results:
- No postoperative deaths occurred across all repeat thoracotomies.
- Median interval between first and second thoracotomy was 23 months.
- Five patients survived over 10 years after initial STS treatment, with some undergoing three or more operations.
Conclusions:
- Repeated thoracotomy is a viable and effective treatment for recurrent lung metastases from STS.
- Complete resection of all metastases during repeat thoracotomy is crucial for favorable long-term survival.
- This approach offers a significant survival benefit for selected patients.