2-Phenethylimidazole derivatives. Synthesis and antimycotic properties

Compounds of type (X = O, NH; Ar and Ar' = phenyl of substituted phenyl; ten examples) were prepared and assayed against miconazole (II,X = O; Ar = Ar' =2,4-Cl2C6H3) as potential antimycotic agents. Optimal activity was noted for I(X = O; Ar = Ar' = 2,4-Cl2C6H3), the direct analog of miconazole. It is about one-tenth as active.