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Immunization against experimental trichinosis using T. spiralis larvae and hydatid fluid antigens
G A el-Ganayni1, A M el-Shazly, H M el-Naggar
1Department of Parasitology, Faculty of Medicine, Mansoura University, Egypt.
Journal of the Egyptian Society of Parasitology
|August 1, 1994
Abstract:
Immunization of mice against T. spiralis infection using T. spiralis larval glycoproteins as homogenous antigen and crude hydatid fluid as heterogenous antigen showed a marked reduction in larvae burden and a significant rise of serum IgE in immunized mice infected with T. spiralis larvae as compared with control group. More reduction was observed with immunization with homogenous T. spiralis larval antigen compared with heterogenous hydatid fluid antigen. The reduction in larval burden with rise of serum IgE begins after the third week of immunization.