Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Personality pattern in peptic ulcer disease: a cohort study

¹Department of Surgical Gastroenterology, Herlev Hospital, University of Copenhagen, Denmark.

Journal of Internal Medicine

|September 1, 1994

Summary

Peptic ulcer disease appears to cause personality changes, not the other way around. This long-term study found no evidence that personality disorders predict peptic ulcers.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Genomic alterations accompanying tumour evolution in colorectal cancer: tracking the differences between primary tumours and synchronous liver metastases by whole-exome sequencing.

BMC cancer·2018

Same author

Health-related quality of life after laparoscopic and open surgery for rectal cancer in a randomized trial.

The British journal of surgery·2016

Same author

Patient-reported genitourinary dysfunction after laparoscopic and open rectal cancer surgery in a randomized trial (COLOR II).

The British journal of surgery·2016

Same author

Reoperation risk following the first operation for internal herniation in patients with laparoscopic Roux-en-Y gastric bypass.

The British journal of surgery·2016

Same author

The prognostic value of lymph node ratio in a national cohort of rectal cancer patients.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2016

Same author

CDX2 downregulation is associated with poor differentiation and MMR deficiency in colon cancer.

Experimental and molecular pathology·2015

Area of Science:

Psychiatry
Gastroenterology
Epidemiology

Background:

Peptic ulcer disease (PUD) is a common gastrointestinal condition.
The relationship between PUD and personality disorders remains unclear.
Previous studies have yielded conflicting results regarding causality.

Purpose of the Study:

To investigate the directionality of the relationship between peptic ulcer disease and personality disorders.
To determine if personality traits precede or follow the development of PUD.

Main Methods:

A 20-year prospective cohort study involving a representative sample of 673 50-year-olds.
Minnesota Multiphasic Personality Inventory (MMPI) assessments were conducted in 1964 and 1974.
Peptic ulcer disease prevalence and incidence were tracked from 1964 to 1984.

Main Results:

Individuals with peptic ulcers in 1964 showed only a slight increase in one neuroticism scale (HS).
Those with prevalent peptic ulcer disease in 1974 exhibited significant increases in multiple neuroticism scales (HS, D, HY) and scales Pd and Pt.
Patients with PUD in 1974 had significantly higher neuroticism scores compared to those without PUD.

Conclusions:

Personality changes observed in patients with peptic ulcer disease are likely a consequence of the condition.
The study suggests that personality disorders do not causally contribute to the development of peptic ulcer disease.
Findings indicate that PUD may lead to psychological distress and altered personality traits.

Related Experiment Videos