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Related Experiment Videos

Rhinoorbital mucormycosis: surgical aspects

S C Bessler1, S Hailemariam, C Gammert

  • 1Department of Otorhinolaryngology, University Hospital of Zurich, Switzerland.

ORL; Journal for Oto-Rhino-Laryngology and Its Related Specialties
|July 1, 1994
PubMed
Summary

Diabetic ketoacidosis with rhinoorbital mucormycosis can be successfully treated by removing necrotic tissue. Early diagnosis and prompt therapy, including antifungal agents, led to a favorable outcome without orbital exenteration.

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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Endocrinology

Background:

  • Diabetic ketoacidosis (DKA) is a serious complication of diabetes mellitus.
  • Rhinoorbital mucormycosis is a rare but aggressive fungal infection, often seen in immunocompromised individuals.

Observation:

  • A young woman presented with diabetic ketoacidosis and rhinoorbital mucormycosis.
  • The infection involved necrotic tissue in the rhino-orbital region.

Findings:

  • Successful treatment was achieved through surgical resection of necrotic areas.
  • The treatment regimen included correction of DKA, debridement, and administration of intravenous and topical amphotericin B.
  • Orbital exenteration was avoided.

Implications:

Related Experiment Videos

  • This case highlights the importance of early diagnosis and aggressive management of rhinoorbital mucormycosis in diabetic patients.
  • Prompt and comprehensive therapy can lead to favorable outcomes and prevent extensive surgical procedures like orbital exenteration.