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Cystic lung disease in Down syndrome
K Gyves-Ray1, S Kirchner, S Stein
1Vanderbilt University Medical Center, Department of Radiology, Nashville, TN 37232-2675.
Pediatric Radiology
|January 1, 1994
Summary
Down syndrome (DS) can cause cystic lung disease, which is often missed on X-rays. CT scans reveal these abnormalities, aiding in understanding their development in children with DS.
Area of Science:
- Pulmonology
- Radiology
- Genetics
Background:
- Down syndrome (DS) is a genetic disorder impacting multiple organ systems.
- Subpleural cystic lung disease is a known pathology in DS patients.
Observation:
- Imaging findings of cystic lung disease in DS are not well-documented in radiology literature.
- Plain chest radiographs may not adequately visualize these pulmonary changes.
Findings:
- A case of extensive cystic lung disease in a child with DS was incidentally discovered via CT scan.
- CT imaging is crucial for identifying subtle cystic lung abnormalities in DS.
Implications:
- This highlights the importance of CT in diagnosing pulmonary manifestations of DS.
- Further research into the pathogenesis of cystic lung disease in DS is warranted.