Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Glandular peripheral nerve sheath tumours

P Robbins1, J Papadimitriou

  • 1Department of Pathology, University of Western Australia, Nedlands.

Pathology, Research and Practice
|April 1, 1994
PubMed
Summary

Glandular peripheral nerve sheath neoplasms are rare tumors. Their behavior depends on the spindle cell stroma, not glandular features, and they require differentiation from other soft tissue tumors.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The burden of end-stage osteoarthritis in Australia: a population-based study on the incidence of total knee replacement attributable to overweight/obesity.

Osteoarthritis and cartilage·2021
Same author

Intracranial monodermal teratoma presenting with growing teratoma syndrome.

Journal of surgical case reports·2017
Same author

Patient factors that influence cerebral desaturation during transcatheter aortic valve implantation.

British journal of anaesthesia·2016
Same author

Immune escape from NY-ESO-1-specific T-cell therapy via loss of heterozygosity in the MHC.

Gene therapy·2014
Same author

Differential regulation of glucose-transporter expression in hematopoietic-cells by oncogenic transformation and cytokine stimulation.

Oncology reports·2011
Same author

Differential-effects of viral and cellular oncogenes on the growth factor-dependency of hematopoietic-cells.

International journal of oncology·2011

Area of Science:

  • Oncology
  • Pathology
  • Genetics

Background:

  • Glandular differentiation in peripheral nerve sheath neoplasms is a rare form of heterologous differentiation.
  • These tumors, termed glandular peripheral nerve sheath neoplasms, are the focus of this review.
  • While often associated with von Recklinghausen's disease and malignancy, benign and sporadic forms exist.

Purpose of the Study:

  • To review glandular peripheral nerve sheath neoplasms.
  • To discuss their characteristics, diagnosis, and prognosis.
  • To clarify their histogenic origins and differentiation from other tumors.

Main Methods:

  • Review of existing literature on glandular peripheral nerve sheath neoplasms.
  • Analysis of histological and immunohistochemical features.
  • Ultrastructural examination for understanding glandular structure origins.

Main Results:

  • The presence and appearance of glandular foci do not influence patient outcome.
  • Prognosis is determined by the spindle cell stroma's nature.
  • Immunohistochemistry and ultrastructural studies aid in diagnosis and understanding origins.

Conclusions:

  • Glandular peripheral nerve sheath neoplasms require careful distinction from tumors like synovial sarcoma.
  • Histogenic origins of glandular structures remain under investigation.
  • Accurate diagnosis relies on assessing stromal components and utilizing advanced diagnostic techniques.

Related Experiment Videos