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Updated: Sep 22, 2026

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents (HPHC)
Published on: May 10, 2016
Unusually high blood cadmium associated with cigarette smoking among three subgroups of the general population,
J L Benedetti1, E Dewailly, F Turcotte
1Centre de toxicologie du Québec, Centre hospitalier de l'université Laval, Canada.
Abstract:
Blood cadmium levels were measured in 554 persons without any known professional exposure to this metal. They were grouped in three samples; one entirely of 142 Inuit, one of 212 caucasian city dwellers and one of 200 caucasian rural residents. While blood cadmium levels measured in non-smokers are comparable to those reported in published reports, those of current cigarette smokers were 10-20 times higher than non-smokers. These blood cadmium values stand in sharp contrast to what has been published so far and make the average smokers of Canadian-made cigarettes medically unfit for employment in jobs associated with potential cadmium exposure.
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