Related Experiment Videos
[Immunologic manifestations in myelodysplastic syndrome]
We describe three patients with primary myelodysplastic syndrome and immunological manifestations. One had painful cutaneous plaques, arthritis and peripheral neuropathy, another showed cutaneous vasculitis, and a third had Sweet's syndrome. All patients responded dramatically to steroids. Before treatment the patient with Sweet's syndrome had high serum levels of interleukin 6 (IL-6), which were reduced to zero after treatment with steroids. Myelodysplastic syndrome should be considered when evaluating patients with immunological or rheumatic manifestations associated with one or more cytopenias.
We describe three patients with primary myelodysplastic syndrome and immunological manifestations. One had painful cutaneous plaques, arthritis and peripheral neuropathy, another showed cutaneous vasculitis, and a third had Sweet's syndrome. All patients responded dramatically to steroids. Before treatment the patient with Sweet's syndrome had high serum levels of interleukin 6 (IL-6), which were reduced to zero after treatment with steroids. Myelodysplastic syndrome should be considered when evaluating patients with immunological or rheumatic manifestations associated with one or more cytopenias.