[Pathogenetic, diagnostic and treatment problems in the cerebral ischemic form of arterial hypertension]

By means of complex investigations we studied the influence of certain brain structures' ischemia caused by disorders of the blood flow through the extracranial arteries on the arterial pressure. We established close correlative dependence between degree of brachycephalic arteries occlusion, contents of biologically active agents in the blood outflowing from the brain (angiotonin-2, vasopressin, prostanoids, catecholamines) and value of systemic arterial pressure. We worked out diagnostic criteria of arterial hypertension cerebroischemic using angio- and dopplerography. We have also substantiated the principles of therapy including inhibitors of angiotonin-converting enzyme and selective blockaders of calcium canals.