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Updated: Jan 20, 2026

Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity
Published on: January 31, 2025
Limb-salvage surgery for treatment of sarcomas of the extremities
1Department of Orthopedic Surgery, Saint Louis University Health Sciences Center, St. Louis, MO 63110.
Abstract:
The management of patients with sarcomas of the appendicular skeleton with limb-sparing surgery has become the standard of care. This is the result of advances in the understanding of the biology and staging of tumors, improvement in reconstructive techniques, and development of effective adjuvant chemotherapy and radiotherapy. A limb-sparing approach is applicable to virtually any bone lesion, whether low grade or high grade, and to all of the common primary soft-tissue sarcomas.
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