Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Retroperitoneal plexiform neurofibromas: CT findings

J C Bass1, M Korobkin, I R Francis

  • 1Department of Radiology, University of Michigan Hospitals, Ann Arbor 48109-0030.

AJR. American Journal of Roentgenology
|September 1, 1994
PubMed
Summary

CT scans reveal characteristic features of retroperitoneal plexiform neurofibromas, typically bilateral, symmetric, low-attenuation masses. Asymmetry in size and attenuation may indicate malignant nerve sheath tumors.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mass-like peripheral zone enhancement on CT is predictive of higher-grade (Gleason 4 + 3 and higher) prostate cancer.

Abdominal imaging·2014
Same author

Renal remodeling in the first 24 months after abdominal radiotherapy.

Practical radiation oncology·2014
Same author

Primary and secondary neoplasms of the spleen.

Cancer imaging : the official publication of the International Cancer Imaging Society·2010
Same author

Mesenteric venous collateral vessels mimicking cystic pancreatic neoplasm.

The British journal of radiology·2010
Same author

Saturation of electroluminescent image-retaining panels by laser beams.

Applied optics·2010
Same author

Computed tomography and magnetic resonance features of renal Ewing sarcoma.

Acta radiologica (Stockholm, Sweden : 1987)·2008

Area of Science:

  • Radiology
  • Oncology
  • Genetics

Background:

  • Retroperitoneal plexiform neurofibromas are rare benign neoplasms.
  • Previous CT findings were limited to case reports.
  • Neurofibromatosis type 1 is a predisposing genetic condition.

Purpose of the Study:

  • Characterize CT features of retroperitoneal plexiform neurofibromas in a larger cohort.
  • Differentiate benign neurofibromas from concurrent malignant nerve sheath tumors.

Main Methods:

  • Retrospective review of CT scans in 25 patients with neurofibromatosis type 1.
  • Identification of 16 patients with suspected plexiform neurofibromas.
  • Biopsy or long-term follow-up for diagnosis confirmation.

Related Experiment Videos

Main Results:

  • Bilateral, symmetric parapsoas masses were seen in 15/16 patients.
  • Presacral and celiac/superior mesenteric artery masses were also identified.
  • Malignant tumors showed asymmetry in size and attenuation.

Conclusions:

  • Retroperitoneal plexiform neurofibromas exhibit characteristic CT findings: bilateral, symmetric, low-attenuation masses.
  • Asymmetry suggests potential malignancy, guiding biopsy decisions.
  • Accurate CT interpretation can prevent unnecessary invasive procedures.