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Related Experiment Videos

Todd's paralysis: A cerebrovascular phenomenon?

P R Yarnell

    Stroke
    |May 1, 1975
    PubMed
    Summary

    Todd

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    Area of Science:

    • Neurology
    • Neuroimaging
    • Epileptology

    Background:

    • Todd's paralysis involves temporary neurological deficits post-seizure.
    • The underlying mechanisms of Todd's paralysis require further elucidation.

    Observation:

    • Angiography sometimes shows correlations between Todd's paralysis and early veins or vascular stains.
    • Radionuclide gamma camera imaging reveals potential hyperperfusion and cortical rim uptake during these events.

    Findings:

    • Focal epileptic discharges may trigger localized vasomotor and metabolic changes.
    • These changes can lead to functional arterial-venous shunting, contributing to cortical ischemia.

    Implications:

    • This provides a potential explanation for a portion of Todd's paralysis cases.
    • Understanding these vascular mechanisms may inform future diagnostic and therapeutic strategies for epilepsy.