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Related Concept Videos

Dementia01:30

Dementia

708
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
708

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A validation study of the Dementia Questionnaire

C Kawas1, J Segal, W F Stewart

  • 1Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Md.

Archives of Neurology
|September 1, 1994
PubMed
Summary

The Dementia Questionnaire effectively screens for dementia in research, showing 100% sensitivity and 90% specificity. This tool aids in identifying cognitive impairment in older adults.

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Area of Science:

  • Gerontology
  • Neurology
  • Psychometrics

Background:

  • Dementia diagnosis requires accurate and efficient screening tools.
  • Informant interviews offer a valuable perspective in assessing cognitive function.

Purpose of the Study:

  • To validate the Dementia Questionnaire, a semistructured informant interview, for diagnosing dementia.
  • To assess the utility of the Dementia Questionnaire in research settings.

Main Methods:

  • A telephone-administered Dementia Questionnaire was compared against a criterion standard of clinical diagnosis.
  • The study included 74 older adults (aged 68-97) from the Baltimore Longitudinal Study of Aging.
  • Sensitivity, specificity, and interrater reliability (kappa coefficient) were calculated.

Main Results:

  • The Dementia Questionnaire demonstrated high diagnostic accuracy with 100% sensitivity and 90% specificity for dementia.
  • False-positive results were primarily associated with cognitive impairment not meeting full dementia criteria.
  • High interrater reliability (kappa = 0.83) was observed.

Conclusions:

  • The Dementia Questionnaire is a valid and reliable tool for screening dementia in research studies.
  • Its high sensitivity and specificity support its use in identifying individuals who may require further clinical evaluation.