Related Experiment Videos
Synthesis and nematocidal activity of arylmercaptovinyltetrahydropyrimidines
N Kraouti1, S Labidalle, R Caujolle
1Département de Chimie, Faculté de Pharmacie, Toulouse.
Farmaco (Societa Chimica Italiana : 1989)
|May 1, 1994
Abstract:
A set of mercaptovinyl tetrahydropyrimidines was synthesized in good yields by lithiation of 1,2-dimethyltetrahydropyrimidine with n-butyl lithium in tetrahydrofurane, followed by condensation with aromatic thioesters. Against three nematode genera, anthelminthic screening shows little activity; 2b and 2d were the most potent against Molinema dessetae.